001 28338
002 3
004 B08C7BD6-EAF8-4C22-92CD-B8E85F53BF07
005 202411040907
008 081223s2012||||xxu#################eng#d
009 1 0
020 ## $a9781848166349
039 ## $y20241104090715 $zdtmkhue
082 ## $a615.2731 $bGO-V
100 $aGouverneur, Véronique
245 ## $aFluorine in pharmaceutical and medicinal chemistry :From biophysical aspects to clinical applications / $cVéronique Gouverneur; Klaus Müller
260 ## $aSingapore : $bImperial College Press, $c2012
300 ## $a546 p. ; $c24 cm
490 ## $aMolecular medicine and medicinal chemistry
520 ## $aFluorine chemistry is an expanding area of research that is attracting international interest, due to the impact of fluorine in drug discovery and in clinical and molecular imaging (e.g. PET, MRI). Many researchers and academics are entering this area of research, while scientists in industrial and clinical environments are also indirectly exposed to fluorine chemistry through the use of fluorinated compounds for imaging.This book provides an overview of the impact that fluorine has made in the life sciences. In the first section, the emphasis is on how fluorine substitution of amino acids, peptides, nucleobases and carbohydrates can provide invaluable information at a molecular level. The following chapters provide answers to the key questions posed on the importance of fluorine in drug discovery and clinical applications
653 ## $aFluorine
653 ## $aPharmaceutical chemistry
852 ## $a10 $bKho Khoa Công nghệ Sinh học $j(15): 10142313-27
890 ## $a15